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Article

Pleiotropic effects of cryptochromes 1 and 2 on free-running and light-entrained murine circadian rhythms.

Journal of neurogenetics - 1 Jan 2000

Van Gelder Russell N, Gibler Therese M, Tu Daniel, Embry Kris, Selby Christopher P, Thompson Carol L, Sancar Aziz

Abstract excerpt

Cryptochromes function in both light entrainment of circadian rhythms and in a peripheral circadian clock mechanism in Drosophila. Mice have two closely related cryptochrome genes (mCry1 and mCry2). To further understand the roles of mammalian cryptochromes, we bred mice to carry all possible combinations of wild-type and cryptochrome knockout alleles, and tested these mice for free-running and entrained...

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Identifiers

PMID: 12696673
DOI: 10.1080/01677060215306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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