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Article

Multidrug resistance 1 gene (P-glycoprotein 170): an important determinant in gastrointestinal disease?

Gut - 1 May 2003

Ho G-T, Moodie F M, Satsangi J

Abstract excerpt

The interface between luminal contents and intestinal epithelium constitutes the largest area of interaction between the host and the environment. There is now strong evidence that the gene product of the multidrug resistant pump (MDR) plays a critical role in host-bacterial interactions in the gastrointestinal tract and maintenance of intestinal homeostasis. This review highlights the efflux mechanism in the...

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Source

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Identifiers

PMID: 12692067
DOI: 10.1136/gut.52.5.759
PMCID: PMC1773632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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