Article
Hepatitis C virus genetic variability: pathogenic and clinical implications.
Clinics in liver disease - 1 Feb 2003
Pawlotsky Jean-Michel
Abstract excerpt
HCV is variable because of the properties of the viral RdRp, high levels of replication, and large population sizes. The Darwinian evolution of HCV has been characterized by the emergence of the HCV genotypes, including six main types and a large number of subtypes. The study of HCV genotype epidemiology provides useful information on the worldwide HCV epidemics. The HCV genotype is an important predictor of the...
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