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Article

Sequence variability of hepatitis C virus and its clinical relevance.

Journal of viral hepatitis - 1 Jan 1994

Dusheiko G, Simmonds P

Abstract excerpt

Chronic type C hepatitis is a potentially serious disease that can lead to cirrhosis and hepatocellular carcinoma. This complex disease is caused by the hepatitis C virus (HCV), a positive sense, single-stranded RNA virus. HCV has been assigned to a separate genus within the Flaviviridae, and shares a close relationship to the pestiviruses. Nucleotide sequence variation has been observed in genomes amplified from...

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PMID: 8790555
DOI: 10.1111/j.1365-2893.1994.tb00057.x

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