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Article

Genetic heterogeneity of hepatitis C virus. The clinical significance of genotypes and quasispecies behavior.

Clinics in laboratory medicine - 1 Jun 1996

Marrone A, Sallie R

Abstract excerpt

Knowledge of the molecular biology of the hepatitis C virus (HCV) has increased exponentially since its identification in 1989. Paradoxically, the understanding of many clinical aspects of HCV pathobiology has lagged behind, partly because of lack of suitable models of disease. The genomic variability of HCV is central to viral pathogenesis. This article briefly reviews some clinical and laboratory aspects of HCV...

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PMID: 8792081

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