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Article

The molecular biology of hepatitis C virus. Genotypes and quasispecies.

Clinics in liver disease - 1 Nov 1999

Forns X, Bukh J

Abstract excerpt

Hepatitis C virus (HCV) is an important cause of chronic liver disease worldwide. HCV is a positive-strand genotype RNA virus with extensive genetic heterogeneity; HCV isolates define 6 major genotypes, and HCV circulates within an infected individual as a number of closely related but distinct species, termed a quasispecies. This article reviews characteristic aspects of HCV molecular biology and their...

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PMID: 11291246
DOI: 10.1016/s1089-3261(05)70234-8

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