Article
Hepatitis C virus genotyping: clinical implications and methods.
Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology - 1 Dec 2001
Nolte F S
Abstract excerpt
Hepatitis C virus (HCV) chronically infects at least 1% of the world's population and is a leading cause of end-stage liver disease. HCV displays a remarkable degree of genomic diversity, with the six major genotypes and numerous subtypes differing in geographic distribution. The ability of this virus to cause persistent infections is a direct result of its genomic plasticity and the evolution of quasispecies...
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