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Article

Simple method to analyze SNP-based association studies using DNA pools.

Genetic epidemiology - 1 May 2003

Visscher Peter M, Le Hellard Stéphanie

Abstract excerpt

Association studies using DNA pools are in principle powerful and efficient to detect association between a marker allele and disease status, e.g., in a case-control design. A common observation with the use of DNA pools is that the two alleles at a polymorphic SNP locus are not amplified in equal amounts in heterozygous individuals. In addition, there are pool-specific experimental errors so that there is...

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PMID: 12687646
DOI: 10.1002/gepi.10240

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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