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Quantitative technologies for allele frequency estimation of SNPs in DNA pools.

Molecular and cellular probes - 1 Dec 2002

Shifman Sagiv, Pisanté-Shalom Anne, Yakir Benjamin, Darvasi Ariel

Abstract excerpt

We have compared several genotyping methods to assess their applicability to single nucleotide polymorphism (SNP) allele frequency estimation in DNA pools. The accuracy of these methods (restriction fragment length polymorphism, real-time pyrophosphate DNA sequencing, single base extension with fluorescently labeled ddNTPs, homogeneous 5'-nuclease assay, and MALDI-TOF mass spectrometry) was tested by calculating...

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PMID: 12490144
DOI: 10.1006/mcpr.2002.0440

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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