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Article

A regulator of G protein signaling-containing kinase is important for chemotaxis and multicellular development in dictyostelium.

Molecular biology of the cell - 1 Apr 2003

Sun Binggang, Firtel Richard A

Abstract excerpt

We have identified a gene encoding RGS domain-containing protein kinase (RCK1), a novel regulator of G protein signaling domain-containing protein kinase. RCK1 mutant strains exhibit strong aggregation and chemotaxis defects. rck1 null cells chemotax approximately 50% faster than wild-type cells, suggesting RCK1 plays a negative regulatory role in chemotaxis. Consistent with this finding, overexpression of...

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Identifiers

PMID: 12686622
DOI: 10.1091/mbc.e02-08-0550
PMCID: PMC153135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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