Article
Chronic lymphocytic leukemia patients with highly stable and indolent disease show distinctive phenotypic and genotypic features.
Blood - 1 Aug 2003
Guarini Anna, Gaidano Gianluca, Mauro Francesca Romana, Capello Daniela, Mancini Francesca, De Propris Maria Stefania, Mancini Marco, Orsini Enrica, Gentile Massimo, Breccia Massimo, Cuneo Antonio, Castoldi Gianluigi, Foa Robert
Abstract excerpt
Different biologic features have been associated with a more or less aggressive clinical course in chronic lymphocytic leukemia (CLL). In the present study, 20 patients with highly stable CLL observed at a single institution over a period of 10 to 23 years and who never required treatment were extensively characterized. The aim was to identify a distinct and reproducible biologic profile associated with disease...
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