Article
Genetic landscape of ultra-stable chronic lymphocytic leukemia patients.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Apr 2018
Raponi S, Del Giudice I, Marinelli M, Wang J, Cafforio L, Ilari C, Piciocchi A, Messina M, Bonina S, Tavolaro S, Bordyuh M, Mariglia P, Peragine N, Mauro F R, Chiaretti S, Molica S, Gentile M, Visentin A, Trentin L, Rigolin G M, Cuneo A, Diop F, Rossi D, Gaidano G, Guarini A, Rabadan R, Foà R
Abstract excerpt
Background: Chronic lymphocytic leukemia (CLL) has a heterogeneous clinical course. Beside patients requiring immediate treatment, others show an initial indolent phase followed by progression and others do not progress for decades. The latter two subgroups usually display mutated IGHV genes and a favorable FISH profile. Patients and methods: Patients with absence of disease progression for over 10 years (10-34)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.