Article
The human tyrosine hydroxylase gene promoter.
Brain research. Molecular brain research - 10 Apr 2003
Kessler Mark A, Yang Ming, Gollomp Kandace L, Jin Hao, Iacovitti Lorraine
Abstract excerpt
13.329 kilobases of the single copy human tyrosine hydroxylase (hTH) gene were isolated from a genomic library. The 5' flanking 11 kilobases fused to the reporter green fluorescent protein (GFP) drove high level expression in TH+ cells of the substantia nigra of embryonic and adult transgenic mice as determined by double label fluorescence microscopy. To provide a basis for future analysis of polymorphisms and...
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