Article
A response element for the homeodomain transcription factor Ptx3 in the tyrosine hydroxylase gene promoter.
Journal of neurochemistry - 1 May 2000
Cazorla P, Smidt M P, O'Malley K L, Burbach J P
Abstract excerpt
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the biosynthesis of catecholamines, which takes place in different types of neuronal systems and nonneuronal tissues. The transcriptional regulation of the TH gene, which is complex and highly variable among different tissues, reflects this heterogeneity. We recently isolated a homeodomain transcription factor, named Ptx3, that is uniquely expressed in the...
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