Article
Transgenic mice expressing yellow fluorescent protein under control of the human tyrosine hydroxylase promoter.
Journal of neuroscience research - 1 Oct 2012
Choi Eun Yang, Yang Jae Won, Park Myung Sun, Sun Woong, Kim Hyun, Kim Seung U, Lee Myung Ae
Abstract excerpt
Pathogenesis of Parkinson's disease and related catecholaminergic neurological disorders is closely associated with changes in the levels of tyrosine hydroxylase (TH). Therefore, investigation of the regulation of the TH gene system should assist in understanding the pathomechanisms involved in these neurological disorders. To identify regulatory domains that direct human TH expression in the central nervous...
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