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Article

Functional consequences of genetic variation in primates on tyrosine hydroxylase (TH) expression in vitro.

Brain research - 8 Sept 2009

Warner Lisa R, Babbitt Courtney C, Primus Alex E, Severson Tonya F, Haygood Ralph, Wray Gregory A

Abstract excerpt

Tyrosine hydroxylase, the rate-limiting enzyme in catecholamine synthesis, is known to contain naturally occurring genetic variation in it's promoter region that associates with a number of neuropsychological disorders. As such, examining non-coding regions is important for understanding tyrosine hydroxylase function in human health and disease. We examined approximately 2 kb upstream of the translation start...

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PMID: 19591812
DOI: 10.1016/j.brainres.2009.06.086

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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