Article
Role of glypican 4 in the regulation of convergent extension movements during gastrulation in Xenopus laevis.
Development (Cambridge, England) - 1 May 2003
Ohkawara Bisei, Yamamoto Takamasa S, Tada Masazumi, Ueno Naoto
Abstract excerpt
Coordinated morphogenetic cell movements during gastrulation are crucial for establishing embryonic axes in animals. Most recently, the non-canonical Wnt signaling cascade (PCP pathway) has been shown to regulate convergent extension movements in Xenopus and zebrafish. Heparan sulfate proteoglycans (HSPGs) are known as modulators of intercellular signaling, and are required for gastrulation movements in...
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