Article
Hoxb13 is required for normal differentiation and secretory function of the ventral prostate.
Development (Cambridge, England) - 1 May 2003
Economides Kyriakos D, Capecchi Mario R
Abstract excerpt
The murine prostate is a structure that is made up of four distinct lobes; the dorsal and lateral prostates (often grouped together as the dorsolateral prostate), the anterior (coagulating gland) and the ventral prostate. Previous work has implicated Hox genes in the development of these structures, but how each lobe acquires unique identities for specific functions has not been addressed. In this study, the...
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