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Article

HOXD13 suppresses prostate cancer metastasis and BMP4 ‐induced epithelial‐mesenchymal transition by inhibiting SMAD1

1 Feb 2021

Abstract excerpt

The HOX genes are a group of highly conserved Homeobox-containing genes that control the body plan organization during development. However, their contributions to tumorigenesis and tumor progression remain uncertain and controversial. Here we provided evidence of tumor-suppressive activity of HOXD13 in prostate cancer. HOXD13 depletion contributes to more aggressiveness of prostate cancer cells in vitro and in...

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Share to Epigenetics and DNA Methylation
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PMID: 33521930
DOI: 10.1002/ijc.33494

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