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Article

Gene dosage-dependent effects of the Hoxa-13 and Hoxd-13 mutations on morphogenesis of the terminal parts of the digestive and urogenital tracts.

Development (Cambridge, England) - 1 Dec 1997

Warot X, Fromental-Ramain C, Fraulob V, Chambon P, Dollé P

Abstract excerpt

Gene targeting experiments have shown that the murine Hoxa-13 and Hoxd-13 paralogous genes control skeletal patterning in the distal region of the developing limbs. However, both genes are also expressed in the terminal part of the digestive and urogenital tracts during embryogenesis and postnatal development. Here, we report the abnormalities occuring in these systems in Hoxa-13(-/-) and Hoxa-13/Hoxd-13 compound...

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Identifiers

PMID: 9428414
DOI: 10.1242/dev.124.23.4781

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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