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Article

Roles of BRCA1 in DNA damage repair: a link between development and cancer.

Human molecular genetics - 1 Apr 2003

Deng Chu-Xia, Wang Rui-Hong

Abstract excerpt

DNA damage causes devastating problems for developing organisms. Recent studies reveal that BRCA1 plays essential roles in homologous recombinational repair, non-homologous end joining, and nucleotide excision repair. BRCA1 mediates these functions by interaction with components of the DNA repair machinery and by regulating expression of genes that are involved in these DNA damage repair pathways. Consequently,...

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Source

Identifiers

PMID: 12668603
DOI: 10.1093/hmg/ddg082

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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