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Article

Changes in rhinovirus protein 2C allow efficient replication in mouse cells.

Journal of virology - 1 Apr 2003

Harris Julie R, Racaniello Vincent R

Abstract excerpt

Rhinovirus type 16 was found to replicate in mouse L cells that express the viral receptor, human intercellular adhesion molecule 1 (ICAM-1). However, infection of these cells at a low multiplicity of infection leads to no discernible cytopathic effect, and low virus titers are produced. A variant virus, 16/L, was isolated after alternate passage of rhinovirus 16 between HeLa and ICAM-1 L cells. Infection of...

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Identifiers

PMID: 12663784
DOI: 10.1128/jvi.77.8.4773-4780.2003
PMCID: PMC152148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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