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Article

HaCaT epithelial cells as an innovative novel model of rhinovirus infection and impact of clarithromycin treatment on infection kinetics.

Virology - 1 Oct 2018

Morgene M Fedy, Maurin Corantin, Pillet Sylvie, Berthelot Philippe, Morfin Florence, Pozzetto Bruno, Botelho-Nevers Elisabeth, Verhoeven Paul O

Abstract excerpt

The in vitro propagation of human rhinoviruses (RVs) is difficult because only few continuous human cell lines are permissive to these agents. We propose an innovative model of epithelial cell infection using a non-transformed continuous keratinocyte line from human origin (HaCaT cells). After infection with RV-A13, RV-A16 or RV-A19, HaCaT cells produced infectious particles without showing any observable...

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Identifiers

PMID: 30077071
DOI: 10.1016/j.virol.2018.07.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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