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Article

Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes.

Circulation research - 2 May 2003

Yoshida Tadashi, Sinha Sanjay, Dandré Frédéric, Wamhoff Brian R, Hoofnagle Mark H, Kremer Brandon E, Wang Da-Zhi, Olson Eric N, Owens Gary K

Abstract excerpt

The interactions between serum response factor (SRF) and CArG elements are critical for smooth muscle cell (SMC) marker gene transcription. However, the mechanisms whereby SRF, which is expressed ubiquitously, contributes to SMC-specific transcription are unknown. Myocardin was recently cloned as a coactivator of SRF in the heart, but its role in regulating CArG-dependent expression of SMC differentiation marker...

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Source

Identifiers

PMID: 12663482
DOI: 10.1161/01.RES.0000068405.49081.09

Genes

SRF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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