Article
Mutation analysis of IgVH gene in B-cell chronic lymphocytic leukemia.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban - 1 Jan 2002
Wang Feng, Zhu Huifen, Zhu Lijuan, Yin Botao, Shen Guanxin
Abstract excerpt
The variable heavy chain region (VH) genes of 3 untreated patients with B-cell chronic lymphocytic leukemia (B-CLL) were cloned and analyzed. The VH family used was VH3-11, VH3-72 and VH3-33. More than 2% difference from the corresponding germline gene was detected in all the 3 obtained potential...
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