Article
IgVH gene mutation status and genomic imbalances in chronic lymphocytic leukaemia with increased prolymphocytes (CLL/PL).
Hematological oncology - 1 Jun 2007
Balogh Zsófia, Reiniger Lilla, Deák Linda, Bödör Csaba, Csomor Judit, Szepesi Agota, Gagyi Eva, Kopper László, Matolcsy András
Abstract excerpt
Chronic lymphocytic leukaemia (CLL) with increased prolymphocytes (CLL/PL) has been defined by the World Health Organization (WHO) classification and considered as a progressive and clinically aggressive variant of CLL. To further characterize the biological features of this disease, we performed IgVH gene mutational status, FISH and high-resolution comparative genomic hybridization (HR-CGH) analysis in 17 cases...
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