Article
RET and NTRK1 proto-oncogenes in human diseases.
Journal of cellular physiology - 1 May 2003
Alberti Luisella, Carniti Cristiana, Miranda Claudia, Roccato Emanuela, Pierotti Marco A
Abstract excerpt
RET and NTRK1 are receptor tyrosine kinase (RTK) proteins which play a role in the development and maturation of specific component of the nervous system. Their alterations have been associated to several human diseases, including some forms of cancer and developmental abnormalities. These features have contributed to the concept that one gene can be responsible for more than one disease. Moreover, both genes...
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