Article
Kin-cohort evaluation of relative risks of genetic variants.
Genetic epidemiology - 1 Apr 2003
Saunders Catherine L, Begg Colin B
Abstract excerpt
The kin-cohort study, an embedded retrospective cohort of first-degree relatives of probands, has been used frequently in conjunction with case-control studies to evaluate penetrance of high-risk genotypes. However, in principle, the kin-cohort approach can be used in conjunction with a case-control study in which family history data are carefully recorded to examine and validate the observed association of any...
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