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Article

Common cancers share familial susceptibility: implications for cancer genetics and counselling.

Journal of medical genetics - 1 Apr 2017

Yu Hongyao, Frank Christoph, Sundquist Jan, Hemminki Akseli, Hemminki Kari

Abstract excerpt

BACKGROUND: It has been proposed that cancer is more common in some families than in others, but the hypothesis lacks population level support. We use a novel approach by studying any cancers in large three-generation families and thus are able to find risks even though penetrance is low. METHODS: Individuals in the nation-wide Swedish Family-Cancer Database were organised in three generations and the relative...

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Source

Identifiers

PMID: 27651446
DOI: 10.1136/jmedgenet-2016-103932

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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