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Article

Power and design considerations for a general class of family-based association tests: quantitative traits.

American journal of human genetics - 1 Dec 2002

Lange Christoph, DeMeo Dawn L, Laird Nan M

Abstract excerpt

In the present article, we address family-based association tests (FBATs) for quantitative traits. We propose an approach to analytical power and sample-size calculations for general FBATs; this approach can be applied to virtually any scenario (missing parental information, multiple offspring per family, etc.). The power calculations are used to discuss optimal choices of the phenotypes for the FBAT statistic...

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Identifiers

PMID: 12454799
DOI: 10.1086/344696
PMCID: PMC378574

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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