Article
A transmission disequilibrium test for quantitative trait loci.
Human heredity - 1 Jan 2000
Rabinowitz D
Abstract excerpt
The transmission disequilibrium test uses association between marker alleles and dichotomous traits for precise genetic mapping while avoiding confounding due to population admixture. Here, the methodology is generalized from dichotomous traits to quantitative traits. The generalization is computationally straightforward and may be used with multiple alleles and with siblings. Parametric assumptions on the...
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