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Article

A unified framework for transmission-disequilibrium test analysis of discrete and continuous traits.

Genetic epidemiology - 1 Jan 2002

Liu Ying, Tritchler David, Bull Shelley B

Abstract excerpt

This paper presents a unified framework for transmission-disequilibrium tests for discrete and continuous traits. A conditional score test is derived that maximizes power to detect small effects for any exponential family distribution, which includes binary and normal distributions, and distributions that are skewed or have non-normal kurtosis. The specific distributional form need not be specified, and the...

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PMID: 11754471
DOI: 10.1002/gepi.1041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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