Identification of CHE-13, a novel intraflagellar transport protein required for cilia formation.

doi:10.1016/s0014-4827(02)00089-7

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Identification of CHE-13, a novel intraflagellar transport protein required for cilia formation.

Experimental cell research - 1 Apr 2003

Haycraft Courtney J, Schafer Jenny C, Zhang Qihong, Taulman Patrick D, Yoder Bradley K

Abstract excerpt

Cilia are present on cells of many eukaryotic organisms and recent data in the mouse suggest that ciliary defects can cause severe developmental abnormalities and disease. Studies across eukaryotic systems indicate that cilia are constructed and maintained through a highly conserved process termed intraflagellar transport (IFT), for which many of the proteins involved have yet to be identified. IFT describes the...

Topics

Amino Acid Motifs
Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Carrier Proteins
Cell Compartmentation
Cells, Cultured
Cilia
DNA, Complementary
DNA-Binding Proteins
Flagella

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Nerve Tissue Proteins

Neurons, Afferent

Neuropeptides

Promoter Regions, Genetic

Protein Transport

Source

Open in PubMed

Identifiers

PMID: 12651157
DOI: 10.1016/s0014-4827(02)00089-7

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12651157-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of CHE-13, a novel intraflagellar transport protein required for cilia formation.PMID 12651157Read ↗

Caenorhabditis elegans DYF-11, an orthologue of mammalian Traf3ip1/MIP-T3, is required for sensory cilia formation.Semantic proximity Read ↗

Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport.Semantic proximity Read ↗

Functional genomics of the cilium, a sensory organelle.Semantic proximity Read ↗

Functional genomics of intraflagellar transport-associated proteins in C. elegans.Semantic proximity Read ↗

The WD repeat-containing protein IFTA-1 is required for retrograde intraflagellar transport.Semantic proximity Read ↗

The C. elegans homolog of the murine cystic kidney disease gene Tg737 functions in a ciliogenic pathway and is disrupted in osm-5 mutant worms.Semantic proximity Read ↗

Sensory ciliogenesis in Caenorhabditis elegans: assignment of IFT components into distinct modules based on transport and phenotypic profiles.Semantic proximity Read ↗

Functional coordination of intraflagellar transport motors.Semantic proximity Read ↗

Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in <i>Caenorhabditis elegans</i>Semantic proximity Read ↗

An essential role for DYF-11/MIP-T3 in assembling functional intraflagellar transport complexes.Semantic proximity Read ↗

IFT-81 and IFT-74 are required for intraflagellar transport in C. elegans.Semantic proximity Read ↗

Elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.