Article
Elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8.
Nature cell biology - 1 Apr 2008
Omori Yoshihiro, Zhao Chengtian, Saras Arunesh, Mukhopadhyay Saikat, Kim Woong, Furukawa Takahisa, Sengupta Piali, Veraksa Alexey, Malicki Jarema
Abstract excerpt
The formation and function of cilia involves the movement of intraflagellar transport (IFT) particles underneath the ciliary membrane, along axonemal microtubules. Although this process has been studied extensively, its molecular basis remains incompletely understood. For example, it is unknown how the IFT particle interacts with transmembrane proteins. To study the IFT particle further, we examined elipsa, a...
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