Article
Acridine mutagenesis of zebrafish (Danio rerio).
Mutation research - 9 Apr 2003
Hampson Richard, Hughes Simon M
Abstract excerpt
Mutagenesis screening, in which heritable traits are isolated following damage to the genome, is a powerful approach for investigating gene function. Among vertebrate model organisms, the zebrafish (Danio rerio) is ideally suited to mutagenesis screens. The success of large-scale screens is dependent on the way in which changes are identified. The type of damage induced is also pivotal. Single base coding region...
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