Article
Induction of mutations in the zebrafish with ultraviolet light.
Genetical research - 1 Apr 1992
Grunwald D J, Streisinger G
Abstract excerpt
Recessive lethal germline and specific locus somatic mutations were induced efficiently in the zebrafish by exposure of mature sperm to UV light. Mutagenesis of sperm yielded mosaic individuals: clones bearing novel mutations represented approximately 12-25% of the haploid germ cells and 25-50% of the somatic tissue. Simple methods are described for the reliable identification and propagation of newly arising...
Topics
- Animals
- DNA Damage
- Female
- Fertility
- Genes, Lethal
- Genotype
- Male
- Mosaicism
- Mutagenesis
- Mutagenesis, Site-Directed
- Phenotype
- Spermatozoa
- Ultraviolet Rays