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Article

A genetic screen for mutations affecting embryogenesis in zebrafish.

Development (Cambridge, England) - 1 Dec 1996

Driever W, Solnica-Krezel L, Schier A F, Neuhauss S C, Malicki J, Stemple D L, Stainier D Y, Zwartkruis F, Abdelilah S, Rangini Z, Belak J, Boggs C

Abstract excerpt

Systematic genome-wide mutagenesis screens for embryonic phenotypes have been instrumental in the understanding of invertebrate and plant development. Here, we report the results from the first application of such a large-scale genetic screening to vertebrate development. Male zebrafish were mutagenized with N-ethyl N-nitrosourea to induce mutations in spermatogonial cells at an average specific locus rate of one...

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Identifiers

PMID: 9007227
DOI: 10.1242/dev.123.1.37

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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