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Article

The role of Wnk4 in polygenic hypertension: a candidate gene analysis on rat chromosome 10.

Hypertension (Dallas, Tex. : 1979) - 1 Apr 2003

Monti Jan, Zimdahl Heike, Schulz Herbert, Plehm Ralph, Ganten Detlev, Hübner Norbert

Abstract excerpt

Linkage analyses in experimental crosses of stroke-prone spontaneously hypertensive (SHRSP) and normotensive Wistar-Kyoto (WKY) rats have strongly suggested the presence of quantitative trait loci (QTL) influencing blood pressure and ACE levels on rat chromosome 10, which have been confirmed in multiple independent studies. Analysis of the orthologous region on human chromosome 17 also revealed significant...

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Source

Identifiers

PMID: 12642508
DOI: 10.1161/01.HYP.0000063147.92433.7D

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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