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Article

Association of WNK1 gene polymorphisms and haplotypes with ambulatory blood pressure in the general population.

Circulation - 29 Nov 2005

Tobin Martin D, Raleigh Stuart M, Newhouse Stephen, Braund Peter, Bodycote Clare, Ogleby Jenny, Cross Deborah, Gracey Jay, Hayes Saija, Smith Terry, Ridge Cathy, Caulfield Mark, Sheehan Nuala A, Munroe Patricia B, Burton Paul R, Samani Nilesh J

Abstract excerpt

BACKGROUND: Blood pressure (BP) is a heritable trait of major public health concern. The WNK1 and WNK4 genes, which encode proteins in the WNK family of serine-threonine kinases, are involved in renal electrolyte homeostasis. Mutations in the WNK1 and WNK4 genes cause a rare monogenic hypertensiv...

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Source

Identifiers

PMID: 16301342
DOI: 10.1161/CIRCULATIONAHA.105.555474

Genes

WNK1
DBP
WNK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16301342-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Association of WNK1 gene polymorphisms and haplotypes with ambulatory blood pressure in the general population.PMID 16301342Read ↗

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