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Article

OM197-MP-AC induces the maturation of human dendritic cells and promotes a primary T cell response.

International immunopharmacology - 1 Mar 2003

Byl B, Libin M, Bauer J, Martin O R, De Wit D, Davies G, Goldman M, Willems F

Abstract excerpt

Dendritic cell (DC) maturation is critical for the induction of antigen-specific T lymphocyte responses and may be essential for the development of human vaccines relying on T cell immunity. We investigated the effects on human DC of OM-197, a synthetic pseudodipeptide derived from amino acids, linked to three fatty acid chains and devoid of endotoxin properties. OM-197 upregulated the expression of HLA-DR, CD80,...

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Identifiers

PMID: 12639819
DOI: 10.1016/S1567-5769(03)00008-0

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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