Article
Characterization of Cu,Zn superoxide dismutase (SOD1) gene knock-out mutant of Cryptococcus neoformans var. gattii: role in biology and virulence.
Molecular microbiology - 1 Mar 2003
Narasipura Srinivas D, Ault Jeffrey G, Behr Melissa J, Chaturvedi Vishnu, Chaturvedi Sudha
Abstract excerpt
The pathogenic yeast Cryptococcus neoformans (Cn) var. gattii causes meningoencephalitis in healthy individuals, unlike the better known Cn varieties grubii and neoformans, which are common in immunocompromised individuals. The virulence determinants and mechanisms of host predilection are poorly defined for var. gattii. The present study focused on the characterization of a Cu,Zn superoxide dismutase (SOD1) gene...
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