Article
Periplasmic superoxide dismutase in meningococcal pathogenicity.
Infection and immunity - 1 Jan 1998
Wilks K E, Dunn K L, Farrant J L, Reddin K M, Gorringe A R, Langford P R, Kroll J S
Abstract excerpt
Meningococcal sodC encodes periplasmic copper- and zinc-cofactored superoxide dismutase (Cu,Zn SOD) which catalyzes the conversion of the superoxide radical anion to hydrogen peroxide, preventing a sequence of reactions leading to production of toxic hydroxyl free radicals. From its periplasmic location, Cu,Zn SOD was inferred to acquire its substrate from outside the bacterial cell and was speculated to play a...
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