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Article

The Cryptococcus neoformans catalase gene family and its role in antioxidant defense.

Eukaryotic cell - 1 Sept 2006

Giles Steven S, Stajich Jason E, Nichols Connie, Gerrald Quincy D, Alspaugh J Andrew, Dietrich Fred, Perfect John R

Abstract excerpt

In the present study, we sought to elucidate the contribution of the Cryptococcus neoformans catalase gene family to antioxidant defense. We employed bioinformatics techniques to identify four members of the C. neoformans catalase gene family and created mutants lacking single or multiple catalase genes. Based on a phylogenetic analysis, CAT1 and CAT3 encode putative spore-specific catalases, CAT2 encodes a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 16963629
DOI: 10.1128/EC.00098-06
PMCID: PMC1563583

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