Article
Zrg1, a cryptococcal protein associated with regulation of growth in nutrient deprivation conditions.
Genomics - 1 Mar 2021
Diehl Camila, Garcia Ane Wichine Acosta, Kinskovski Uriel Perin, Sbaraini Nicolau, Schneider Rafael de Oliveira, Ferrareze Patricia Aline Gröhs, Gerber Alexandra Lehmkuhl, de Vasconcelos Ana Tereza Ribeiro, Kmetzsch Livia, Vainstein Marilene Henning, Staats Charley Christian
Abstract excerpt
Cryptococcus gattii is one of the causes of cryptococcosis, a life-threatening disease generally characterized by pneumonia and/or meningitis. Zinc is an essential element for life, being required for the activity of many proteins with catalytic and structural roles. Here, we characterize ZRG1 (zinc-related gene 1), which codes a product involved in zinc metabolism. Transcriptional profiling revealed that zinc...
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