Article
Modulation of smooth muscle phenotype in vitro by homologous cell substrate.
American journal of physiology. Cell physiology - 1 Jun 2003
Tao F, Chaudry S, Tolloczko B, Martin J G, Kelly S M
Abstract excerpt
We have developed a novel cell culture system that supports the shortening of smooth muscle cells. Primary rat airway smooth muscle cells were plated on an ethanol-fixed, confluent monolayer of homologous smooth muscle cells (homologous cell substrate, HCS). Cells grown on HCS exhibited morphological and functional characteristics consistent with a differentiated phenotype. Cells on HCS were spindle shaped with a...
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