Distribution of phenotypically disparate myocyte subpopulations in airway smooth muscle.

doi:10.1139/y04-128

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Article

Distribution of phenotypically disparate myocyte subpopulations in airway smooth muscle.

Canadian journal of physiology and pharmacology - 1 Jan 2005

Halayko Andrew J, Stelmack Gerald L, Yamasaki Akira, McNeill Karol, Unruh Helmut, Rector Edward

Abstract excerpt

Phenotype and functional heterogeneity of airway smooth muscle (ASM) cells in vitro is well known, but there is limited understanding of these features in vivo. We tested whether ASM is composed of myocyte subsets differing in contractile phenotype marker expression. We used flow cytometry to compare smooth muscle myosin heavy chain (smMHC) and smooth muscle-alpha-actin (sm-alpha-actin) abundance in myocytes...

Topics

Actins
Animals
Bronchi
Cell Proliferation
Cells, Cultured
Dogs
Female
Flow Cytometry
Fluorescent Antibody Technique
Humans
Male
Microscopy, Confocal
Myocytes, Smooth Muscle
Myosin Heavy Chains
Phenotype
Trachea

Source

Open in PubMed

Identifiers

PMID: 15759057
DOI: 10.1139/y04-128

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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