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Article

The effects of stretch on vascular smooth muscle cell phenotype in vitro.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology - 1 Jan 2000

Halka Anastassi T, Turner Neill J, Carter Andrew, Ghosh Jonathan, Murphy Michael O, Kirton John P, Kielty Cay M, Walker Michael G

Abstract excerpt

Vascular smooth muscle cells (VSMC) situated in the tunica media of veins and arteries are central to maintaining conduit integrity in the face of mechanical forces inherent within the cardiovascular system. The predominant mechanical force influencing VSMC structural organisation and signalling is cyclic stretch. VSMC phenotype is manipulated by externally applied stretch which regulates the activity of their...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mechanotransduction, Cellular

Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

Share to rho GTP-Binding Proteins

Share to Stress, Mechanical

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Source

Identifiers

PMID: 18329554
DOI: 10.1016/j.carpath.2007.03.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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