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Article

Phenotypic modulation of primary vascular smooth muscle cells by short-term culture on micropatterned substrate.

PloS one - 1 Jan 2014

Chang Soyoung, Song Seungjeong, Lee Jungsul, Yoon Jonghee, Park Junseong, Choi Sungyoung, Park Je-Kyun, Choi Kyungsun, Choi Chulhee

Abstract excerpt

Loss of contractility and acquisition of an epithelial phenotype of vascular smooth muscle cells (VSMCs) are key events in proliferative vascular pathologies such as atherosclerosis and post-angioplastic restenosis. There is no proper cell culture system allowing differentiation of VSMCs so that it is difficult to delineate the molecular mechanism responsible for proliferative vasculopathy. We investigated...

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Identifiers

PMID: 24505388
DOI: 10.1371/journal.pone.0088089
PMCID: PMC3913720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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