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Article

Phenotypic changes in cultured smooth muscle cells: limitation or opportunity for tissue engineering of hollow organs?

Journal of tissue engineering and regenerative medicine - 1 Jul 2012

Huber Alexander, Badylak Stephen F

Abstract excerpt

Smooth muscle cells (SMCs) are typically used as a cell source for the reconstruction of hollow organs by conventional tissue engineering techniques. However, the necessity for and advantage of the use of tissue-specific SMCs are unknown. The present study investigated the phenotypic changes that occur following isolation and in vitro expansion of rat SMC populations isolated from three different tissues: the...

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PMID: 21755602
DOI: 10.1002/term.451
PMCID: PMC3237740

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