Article
Association of the CTLA4 promoter region (-1661G allele) with type 1 diabetes in the South Moroccan population.
Genes and immunity - 1 Mar 2003
Bouqbis L, Izaabel H, Akhayat O, Pérez-Lezaun A, Calafell F, Bertranpetit J, Comas D
Abstract excerpt
The contribution of the candidate gene CTLA4 to type 1 diabetes is not well established. Although several polymorphisms have been repeatedly associated to the disease, several studies have not confirmed the association. The joint analysis of three SNPs in the CTLA4 promoter region (-1722, -1661, and -319), one SNP in the first exon (+49), and one dinucleotide repeat in the 3' untranslated region, in a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
